How sensitive and specific is continuous wave Doppler for detecting peripheral arterial disease in people with and without diabetes? A cross-sectional study

Tehan, Peta Ellen; Sebastian, Mathew; Barwick, Alex Louise; Chuter, Vivienne Helaine

Title: How sensitive and specific is continuous wave Doppler for detecting peripheral arterial disease in people with and without diabetes? A cross-sectional study
Creator: Tehan, Peta Ellen; Sebastian, Mathew; Barwick, Alex Louise; Chuter, Vivienne Helaine
Relation: Diabetes and Vascular Disease Vol. 15, Issue 5, p. 396-401
Publisher Link: http://dx.doi.org/10.1177/1479164118782887
Publisher: Sage
Resource Type: journal article
Date: 2018
Description: Background: Continuous-wave Doppler is frequently used for detecting peripheral arterial disease in patients with diabetes; however, there is limited evidence investigating diagnostic accuracy. This study aimed to determine sensitivity and specificity of continuous-wave Doppler for detecting peripheral arterial disease in populations with, and without, diabetes and to investigate the influence of disease severity on sensitivity of continuous-wave Doppler for detecting peripheral arterial disease. Results: Data from 396 participants were included. Using colour Duplex ultrasound as reference standard (N=66), printed continuous-wave Doppler waveform analysis sensitivity was 81.75% (95% confidence interval: 76.75 to 85.88) and specificity 89.34% (95% confidence interval: 82.62 to 93.67). Printed continuous-wave Doppler waveform analysis sensitivity for peripheral arterial disease was comparable to sensitivity calculated using angiography as the reference standard (81.67%; 95% confidence interval: 69.56 to 90.48). Sensitivity and specificity were unaffected by diabetes diagnosis (n = 176), sensitivity 82.76% (95% confidence interval: 74.86 to 88.55), and specificity 88.33% (95% confidence interval: 77.82 to 94.23). Conclusion: Continuous-wave Doppler is a fair assessment tool for peripheral arterial disease in a community-based sample with suspected peripheral arterial disease. Diagnostic accuracy of continuous-wave Doppler for peripheral arterial disease is unaffected by the presence of diabetes.
Subject: peripheral arterial disease; duplex ultrasound; angiograph; continuous-wave Doppler; sensitivity; specificity; diagnostic accuracy
Identifier: http://hdl.handle.net/1959.13/1446069
Identifier: uon:42754
Identifier: ISSN:1752-8984
Language: eng
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